A study of three doses of ici 35 868 for induction and maintenance of anaesthesia.
نویسندگان
چکیده
Three doses (1.5, 2.0 and 2.5 mg kg-1) of diisopropyl phenol (ICI 35 868) were compared for induction and maintenance of anaesthesia in healthy females undergoing short gynaecological procedures. Induction of anaesthesia was smooth and rapid. Cardiovascular changes (which were dose-dependent) included a decrease in arterial pressure and an increase in heart rate. These changes were magnitudes comparable to those reported for other induction agents. Recovery from the effects of the drug was rapid and uneventful.
منابع مشابه
Comparison of the respiratory effects of ICI 35 868 and thiopentone in the rabbit.
The effects of thiopentone and ICI 35 868 on minute volume, respiratory frequency, tidal volume and arterialized venous PCO2, pH and standard bicarbonate have been compared in the rabbit. ICI 35 868 has two to three times the potency of thiopentone, but equivalent anaesthetic doses cause similar decreases in minute volume. ICI 35 868 decreased tidal volume to a greater extent than thiopentone. ...
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ورودعنوان ژورنال:
- British journal of anaesthesia
دوره 53 3 شماره
صفحات -
تاریخ انتشار 1981